Forschungs-Reagenzien
A novel type of influenza A virus-derived Defective interfering Particle for antiviral therapy
Ref.-Nr.: 1402-5459-BC
Forschungs-Reagenzien : Antikörper
Human influenza A virus (IAV) is responsible for seasonal disease in people and can cause worldwide pandemics. The main lines of defense against IAV are vaccines and antiviral drugs.
Influenza vaccines, including killed and live vaccines, recombinant virus-like particles and viral particles, have been available commercially for many years. Typically, the composition of influenza vaccines is based on the major influenza virus strains causing infection in the previous season. Accordingly, ...
Cyclopropenylylidene-Stabilized Phosphenium Cations and their Applications in Homogeneous Catalysis
Ref.-Nr.: 0042-5177-LC-WA
Prozesse und Methoden (inkl. Screening) : Chemische
Forschungs-Reagenzien : Andere
Neue Materialien
We offer novel phosphenium ligands and corresponding metal complexes (both air stable) that are claimed as substances by granted EP and US patents. The ligands can be prepared in multigram scale by simple direct condensation. The corresponding gold complexes are suitable as homogeneous catalysts in organic synthesis (such as cycloisomerization) that can be easily precipitated and recycled due to their salt properties.
Do you need to shut down protein synthesis reversibly and in a cell-type specific manner?
Ref.-Nr.: 0602-5504-LI
Prozesse und Methoden (inkl. Screening) : Lebens-Wissenschaften (inkl. Screening)
Forschungs-Reagenzien : Andere
Nukleinsäure-, Protein-, Zell-bezogene Technologien : Nukleinsäure (bezogen)
A precise and genetically encoded inhibitor for cell-type selective, inducible and reversible inhibition of protein synthesis
N-substituted pyridiniophosphines, processes for their preparation and their use
Ref.-Nr.: 0042-4938-LC-WA
Prozesse und Methoden (inkl. Screening) : Chemische
Forschungs-Reagenzien : Andere
Neue Materialien
We offer a new family of cationic ligands, namely N-alkyl/aryl pyridiniophosphines. The ligands can be synthesized through a short, scalable, and highly modular route.
Evaluation of their electronic properties evidenced weak σ-donor and quite strong π-acceptor character when used as ancillary ligands.
Weiterlesen … N-substituted pyridiniophosphines, processes for their preparation and their use
Novel Biomarkers for Ageing and Metabolic Health
Ref.-Nr.: 1013-5354-MSG
Analytik
Medizin : Therapeutika
Medizin : Diagnostika
Forschungs-Reagenzien : Andere
Nukleinsäure-, Protein-, Zell-bezogene Technologien : Zellen (bezogen)
Biomarkers of ageing have long been sought after to help assess the biological age and general health status of individuals. Considerable efforts have been invested to identify such biomarkers, including physiologic readouts, metabolic parameters, glycomic profiles and others. Nevertheless, markers with strong predictive power have remained elusive.
Work in model organisms has identified several conserved signaling pathways that extend life span, such as reduced insulin/IGF signaling and ...
Weiterlesen … Novel Biomarkers for Ageing and Metabolic Health
RNA-CASing: means and methods for selective isolation and stabilization of RNA molecules
Ref.-Nr.: 0706-5433-MSG
Prozesse und Methoden (inkl. Screening) : Lebens-Wissenschaften (inkl. Screening)
Forschungs-Reagenzien : Andere
Nukleinsäure-, Protein-, Zell-bezogene Technologien : Nukleinsäure (bezogen)
RNACasing: A novel and selective way of isolating and stabilizing RNA molecules, which enables processing, storing and shipping of RNA at room temperature.
SUMOvera: A Truly Orthogonal Cleavage Module
Ref.-Nr.: 0402-5439-LI
Prozesse und Methoden (inkl. Screening) : Lebens-Wissenschaften (inkl. Screening)
Forschungs-Reagenzien : Andere
Nukleinsäure-, Protein-, Zell-bezogene Technologien : Protein (bezogen)
SUMOvera enables versatile purification strategies for broad applications in eukaryotic hosts.
Thioimidazolium ionic liquids as non-volatile and derivatizable alkylating reagents
Ref.-Nr.: 0401-5411-LC-WA
Prozesse und Methoden (inkl. Screening) : Chemische
Forschungs-Reagenzien : Andere
Neue Materialien
The offered thioimidazolium ionic liquids are a class of easily synthesized and harnessed alkylating agents that are completely non-volatile. The active alkylating species is produced in-situ, thus eliminating exposure and the need for specialized equipment. These features can also be used in the solid-state by their attachment to a poly(styrene) support, which allows for easy purification of the product and regeneration of the thioimidazolium alkylator and could be of special interest for flow ...
Weiterlesen … Thioimidazolium ionic liquids as non-volatile and derivatizable alkylating reagents